NAD+ (Nicotinamide Adenine Dinucleotide) Injection Dosage Guide
Disclaimer: Always consult a healthcare professional before beginning NAD+ therapy. Dosage can vary based on individual needs, health goals, and underlying conditions.
What is NAD+?
NAD+ is a coenzyme essential for cellular energy production and mitochondrial function. It is commonly used for anti-aging, improved mental clarity, increased energy, addiction recovery, and metabolic optimization.
Forms of Administration:
- Subcutaneous (SubQ) or Intramuscular (IM) injection
- IV (for higher doses under medical supervision)
General Dosage Guidelines:
1. Low-Dose Maintenance Therapy:
- Purpose: General wellness, anti-aging, and boosting energy
- Dose: 50 mg to 150 mg, 2-3 times per week
- Administration: SubQ or IM injection
- Duration: Long-term use (e.g., 2-3 months, then reevaluate)
2. Moderate-Dose for Enhanced Energy and Cognitive Function:
- Purpose: Mental clarity, fatigue, recovery from stress
- Dose: 250 mg to 500 mg per injection, 1-2 times per week
- Administration: IM or SubQ (administer slowly to minimize discomfort)
- Duration: Typically 4-8 weeks followed by a maintenance phase
3. High-Dose (Detox, Addiction Recovery, or Intensive Anti-Aging Therapy):
- Purpose: Addiction recovery, accelerated detoxification, mitochondrial repair
- Dose: 500 mg to 1,000 mg per injection, 3-5 times per week
Administration:
- IM or SubQ (split the dose if injecting >500 mg to reduce discomfort)
Duration: 7-14 days for intensive therapy, then transition to lower maintenance doses
Injection Instructions:
- Syringe Type: Use an insulin or small-gauge syringe for SubQ injections
- Injection Sites:
- SubQ: Abdomen, thigh, or upper arm
- Injection Speed: Administer slowly to reduce discomfort and nausea (especially for higher doses)
Storage:
- Store reconstituted NAD+ solution in the refrigerator (36°F to 46°F / 2°C to 8°C) and protect it from light.
- Do not freeze. Use reconstituted solutions within the timeframe recommended by the manufacturer.
Common Side Effects and Management:
- Nausea, headache, muscle fatigue: Reduce the dose or slow the injection rate.
- Injection site irritation: Rotate injection sites and ensure proper sterilization.
- Flushing or mild dizziness: Take breaks between higher doses or split large injections into smaller portions.
Recommended Supplements (for enhanced effectiveness):
- Tryptophan or Nicotinamide Mononucleotide (NMN): Supports NAD+ synthesis.
- CoQ10 and L-Carnitine: Enhance mitochondrial function.
- Electrolytes (potassium, magnesium): Help reduce muscle fatigue and cramps.
Special Considerations:
- Hydration: Ensure proper hydration before and after injection.
- Monitoring: If using NAD+ for therapeutic purposes (e.g., addiction recovery), regular supervision and lab tests may be necessary.
- Gradual Increase: Begin with lower doses and gradually increase as tolerated to avoid nausea or fatigue.
Sample Protocol for General Use:
Week |
Dosage (per injection) |
Frequency |
---|---|---|
1 |
50 mg |
2-3x per week |
2-4 |
150 mg |
2-3x per week |
5+ |
250 mg or as needed |
1-2x per week (maintenance) |
For intensive treatment:
Duration |
Dosage (per injection) |
Frequency |
---|---|---|
7-14 days |
500-1,000 mg |
3-5x per week |
Note: Higher doses (e.g., >500 mg) are generally given via IV infusion in clinical settings. Ensure any high-dose protocol is medically supervised.
Always consult a healthcare provider to determine the appropriate dose for your health needs.